An improved solubility test for haemoglobin S.

Present day practice An improved solubility test for haemoglobin

Because conventional methods of testing for sickling are time consuming and liable to error other tests have been suggested for the detection of haemoglobin S (Hb S) (Ballard, Radel, Sakhadeo, and Schorr, 1970; Canning and Huntsman, 1970; Huntsman, Barclay, Canning, and Yawson, 1971; Cook and Raper, 1971). Most of these solubility tests for Hb S are adaptations of the quantitative precipitation...

False positive results with a rapid solubility test for haemoglobin S.

Rapid solubility test for detection of hemoglobin S.

Several screening methods for detecting sickling hemoglobins are presently used in the clinical laboratory (1-6). The present procedure depends on the insolubility of reduced hemoglobin S in a 2.24 mol/liter phosphate buffer. The commercially available “Sickledex” (Ortho Diagnostics, Raritan, N.J. 08869) is also thought to be based on this principle (6). Our method was compared with the standar...

An improved test for phenylketonuria.

HENYLKETONURIA (phenylpyruvic oligophrenia) is a metabolic disorder first recognized by Foiling (1) approximately 25 years ago. He found that two mentally retarded children in. the same family excreted urine containing a substance which gave a green color with ferric chloride. This substance was identified as phenylpyruvic acid. It has subsequently been recognized that in phenylketonuria a bloc...

Phased array ultrasonic imaging using an improved beamforming based total focusing method for non destructive test

One of the novel ultrasonic phased array based scanning methods for ultrasonic imaging in non-destructive test is total focusing method (TFM). This method employs maximum available information of the phased array elements and leads to an improved defect detection accuracy compared to conventional scanning methods. Despite its high detection accuracy, TFM behaves weak in distinguishing the real ...